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Provided these precautions are observed, it should be safe for use during pregnancy and lactation

Signaling pathways involved in regulating MMPs transcription mainly include mitogen-activated protein kinase (MAPK), 101,109,110 reactive oxygen species (ROS), 111 adenosine 5-monophosphate-activated protein kinase (AMPK), 112,113 extracellular-signal-regulated kinase (ERK), 114 JUN N-terminal kinase (JNK) etc

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Current evidence suggests a possible association

Alongside its potent efficacy, it also offers an exceptionally favorable safety profile